LSU Hospitals

Media Sweep

 

Friday, June 12, 2009

 

LSU and Our Lady of the Lake Discussions for Graduate Medical Education Move Forward

LSU Health Care Services Division | 06.12.09

 

Lake may become teaching hospital

The Advocate | 06.12.09

 

LSU's teaching hospital in BR could move to Our Lady of the Lake

The Times-Picayune | 06.12.09

 

Proposal to delay hospital is halted

The Times-Picayune | 06.12.09

 

LSU Health Sciences Center Research Finds Single Gene Controls Growth of Some Cancers

AScribe | 06.11.09

 

Editorial: Protect education, health care

Daily World | 06.12.09

 

Tables turned on budget

LaPolitics Weekly | 06.12.09

 

House agrees with Senate budget but won't back funding

The Town Talk | 06.12.09

 

Landrieu accused of mixing messages on health care

The Times-Picayune | 06.12.09

 

Budget passes House, but with a twist

WAFB | 06.11.09

 

Former Senate secretary, lawyer Michael Baer, dies

The Advocate | 06.12.09

 

To Flu Experts, ‘Pandemic’ Confirms the Obvious

The New York Times | 06.11.09

 

Medicine in the Age of Twitter

The New York Times | 06.11.09

 

Senate Approves Tight Regulation Over Cigarettes

The New York Times | 06.11.09

 

Drug Appears Safe for Morning Sickness

The New York Times | 06.11.09

 

How a Mild Virus Might Turn Vicious

The New York Times | 06.11.09

 

Can Memory Loss Be Prevented?

The New York Times | 06.11.09

 

 

LSU and Our Lady of the Lake Discussions for Graduate Medical Education Move Forward

LSU Health Care Services Division | 06.12.09

 

Baton Rouge, LALouisiana State University and Our Lady of the Lake Regional Medical Center today agreed to a non-binding Memorandum of Understanding (MOU) that creates a public-private collaboration between the two organizations and outlines relocation of certain Baton Rouge based Graduate Medical Education programs to Our Lady of the Lake’s campus.

 

“This accord is a step in the right direction.  It moves graduate   medical education to a higher level and enhances health care delivery for LSU and residents of the Baton Rouge Region,” said LSU System President Dr. John V. Lombardi.  “The Jindal administration, including the Department of Health and Hospitals, has strongly encouraged this private-public relationship as a model for health care effectiveness.”

 

This agreement provides for LSU to relocate a number of inpatient Graduate Medical Education programs from the Earl K. Long Medical Center to the OLOL hospital campus on Essen Lane. With the move of certain of its physician training programs, certain inpatients currently seen at Earl K. Long will be admitted to LSU’s teaching service at the OLOL campus. OLOL will expand its inpatient capacity by a minimum of 60 beds and will work to expand the current Trauma Center at the Essen Lane campus.

 

LSU will expand its outpatient clinics currently in operation.  The LSU Health System North Baton Rouge Clinic, the new state-of-the-art facility recently opened on Airline Highway, will add a 24-hour urgent care clinic for patients who currently seek non-emergency or primary care in the ER.

 

OB services and care for prisoners will not be provided at OLOL.  Both LSU and OLOL will continue to work with the Department of Health and Hospitals and the Capitol Area Human Services District to maintain current levels of psychiatric care in the Baton Rouge area.

 

“Both LSU and OLOL recognize that this successful collaboration is dependent on certain commitments from the state of Louisiana. This now actually becomes a three-way discussion. Everyone is aware of the current state budget constraints as well as the challenges and opportunities within an uncertain national landscape of healthcare financing, so the funding model must be sustainable in the long term,” said Scott Wester, CEO, Our Lady of the Lake. “Our goal is to make sure we have doctors trained in and for Louisiana for the foreseeable future.”

 

The MOU spells out that LSU would purchase or build a Medical Education Building on or near the Our Lady of the Lake campus to be used by faculty, residents, fellows and medical students.

 

“We are excited about this proposed public-private collaboration,” said DHH Secretary Alan Levine.  “It’s an innovative model that makes sense for LSU, for Baton Rouge and, potentially, for other parts of the state, where we are looking for ways to sustain access to inpatient care, expand the availability of much-needed primary and preventive services, and enhance graduate medical education to train a first-class physician workforce for the future.  I commend the forward-thinking vision of LSU and the leadership of Our Lady of the Lake.  This type of collaboration requires a willingness to think not about the past, but about the future.”

 

The proposal requires the commitment of the Department of Health and Hospitals for necessary sustainable funding through a combination of federal and state funding sources in order to provide care for these inpatients by the LSU teaching service relocated to the OLOL campus.

 

“The MOU demonstrates LSU’s dedication to pursue every avenue available in providing the best possible graduate medical education,” said Dr. Fred Cerise, LSU System vice president for health affairs and medical education.  “This collaboration with Our Lady of the Lake also will maintain the high quality health care LSU patients receive in all our hospitals.”

 

The next steps in the discussions will include further evaluation of the financial and patient volume impact of the collaboration as well as facility planning and governance. This MOU sets the stage for a more formal agreement called a Cooperative Endeavor Agreement or CEA, which will be a three-party agreement between the state, LSU and OLOL. After a CEA is agreed upon, it is anticipated that LSU’s physician training programs will be relocated to OLOL in the next two years.

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Lake may become teaching hospital

The Advocate | 06.12.09

By MARSHA SHULER

Advocate Capitol News Bureau

 

A proposed deal in which Our Lady of the Lake Regional Medical Center would become LSU’s Baton Rouge teaching hospital could be completed by Sept. 30, officials involved in the negotiations announced Thursday.

 

LSU and Our Lady of the Lake officials signed a memorandum of understanding late Wednesday. The memo outlines the responsibilities of each party in a potential public-private partnership.

 

The next step is the signing of a cooperative endeavor agreement, which would seal the deal.

 

Gov. Bobby Jindal and health chief Alan Levine support the partnership, which would ultimately lead to the closure of LSU’s antiquated Earl K. Long Medical Center.

 

LSU operates medical education programs that train future physicians at Earl K. Long in north Baton Rouge. The hospital serves the area’s poor and uninsured.

 

Under the agreement, training programs and inpatient care would move to the Lake, which is on Essen Lane near Interstate 10.

 

The memorandum of understanding sets Sept. 30 as the goal for reaching a “binding” agreement that includes a state pledge of financial support for the arrangement.

 

The Legislature next week would be asked to endorse a resolution that outlines LSU’s intentions to continue negotiations, said LSU System vice president Fred Cerise. The Legislature’s budget panel must approve a final deal when it is inked.

 

“It’s not time for people to start showing up at the Lake,” Cerise said. “We are moving forward … but we are still a ways away from a move.”

 

Cerise and the Lake’s CEO Scott Wester said progress is being made on working out complicated federal and state health-care financing issues related to medical education and hospital care reimbursement. Both are key to the collaboration’s success, they said.

 

In addition, the agreement requires financing of an estimated $125 million in capital construction. Included are construction or purchase of a medical education building on the Lake campus off Essen Lane, a 60-bed hospital addition and expansion of the facility’s trauma center.

 

“The state needs to work with both parties to make a commitment to make sure this can happen,” said the Lake’s CEO Scott Wester. “The funding model must be sustainable in the long-term.”

 

If a final agreement is struck, Wester said it would probably take two-plus years before the Lake could construct additional bed capacity to allow transition of LSU patients to occur.

 

LSU and the Lake announced they had entered into serious discussions last December. At the time, LSU shelved plans to build a new $300 million public hospital.

 

Under the recently signed memo, LSU would continue to operate its out-patient clinics in the Baton Rouge area and expand them to meet community needs. Included would be the addition of a 24-hour urgent care center at LSU’s new state-of-the-art north Baton Rouge clinic — located near Earl K. Long.

 

State Sen. Sharon Broome, D-Baton Rouge, in whose district EKL sits, made a pitch last week to Jindal for the urgent care center funding.

 

Left open is the possibility of an approximately 15,000-square-foot clinic for LSU to be located on or near the Lake’s campus. It would be owned by the Lake and leased to LSU.

 

Prisoner care and obstetrical services would not be located at the Lake. LSU would have to enter into other contractual arrangements for alternative locations.

 

The initial term of any cooperative endeavor agreement reached would be at least five years, or a period of time equal to the longest residency program.

 

http://www.2theadvocate.com/news/47889032.html?index=14&c=y.

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LSU's teaching hospital in BR could move to Our Lady of the Lake

The Times-Picayune | 06.12.09

by The Associated Press

 

BATON ROUGE, La. (AP) -- A Catholic-operated hospital would become LSU's Baton Rouge teaching hospital and get $125 million in improvements under a proposal that would ultimately close the public hospital in Baton Rouge.

 

Officials say a memorandum of understanding with Our Lady of the Lake Regional Medical Center was signed late Wednesday, and the proposed public-private partnership could be completed by Sept. 30.

 

Gov. Bobby Jindal and health chief Alan Levine support the partnership.

 

LSU now uses Earl K. Long Hospital, which serves the area's poor and uninsured.

 

Training programs and inpatient care would move to the Lake under the agreement. It would require financing an estimated $125 million in capital construction, including a medical education building, 60 new beds and expanding the trauma center.

 

http://www.nola.com/news/index.ssf/2009/06/lsus_teaching_hospital_in_br_c.html

 

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Proposal to delay hospital is halted

The Times-Picayune | 06.12.09

By Bill Barrow

Capital bureau

 

BATON ROUGE -- The Senate Education Committee buried a bill that would have put the brakes on the state acquiring land for the proposed teaching hospital slated to be built in lower Mid-City, requiring a new legislative review of a financing plan.

 

After sailing through the House earlier this session, House Bill 780 by Rep. Rick Nowlin, R-Natchitoches, ran into a 7-1 buzzsaw, led by Sen. Ann Duplessis, D-New Orleans, who disputed the notion that the bill was designed to protect private property rights.

 

"This bill is more about the new hospital being focused at Charity Hospital," she said, referring to some of the bill's backers who oppose the lower Mid-City site and want the state to gut Charity and rebuild within its shell.

 

Duplessis also pointedly asked Nowlin, "Are you from New Orleans?"

 

Nowlin said private property rights, the importance of medical education across Louisiana and the hospital's advertised $1.2 billion price tag -- with $300 million in state money already committed -- made it acceptable for a northern Louisiana lawmaker to weigh in.

 

State Treasurer John Kennedy, a critic of the hospital planning, said, "I don't see this as a New Orleans bill or a health care bill. This is an expropriation bill. . . . We shouldn't take land until we know we can build a hospital."

 

Jerry Jones, the state facilities chief who is planning the project along with Louisiana State University System executives, found senators sympathetic that Nowlin's bill would cause a delay in the project.

 

Fred Cerise, vice president of the LSU System, showed lawmakers copies of two previous business plans that the Legislature's Joint Budget Committee has already approved, including the latest version released in mid-2008 with Jindal's backing.

 

Sen. Eric LaFleur, D-Ville Platte, cast the lone vote in support of Nowlin's measure. LaFleur questioned why the state couldn't delay land closings and takings -- given that it awaits a resolution of its dispute with the federal government over how much the Federal Emergency Management Agency will pay for Charity Hospital damage caused by Hurricane Katrina. The outcome of that decision also will influence how much of the construction budget will come from bonds backed by future hospital revenues.

 

Jones confirmed for LaFleur that the bonds -- whatever the amount -- would not be sold until after the state knows how much FEMA is chipping in.

 

http://www.nola.com/news/t-p/capital/index.ssf?/base/news-7/124478465082910.xml&coll=1

 

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LSU Health Sciences Center Research Finds Single Gene Controls Growth of Some Cancers

AScribe | 06.11.09

Leslie Capo

 

NEW ORLEANS, June 11 (AScribe Newswire) -- Research led by Ashok Aiyar, PhD, Associate Professor of Microbiology at LSU Health Sciences Center New Orleans, showing that a single gene can control growth in cancers related to the Epstein-Barr virus and that existing therapeutics can inactivate it, will be published in the June 12, 2009 online issue of PLoS Pathogens.

 

The Epstein-Barr virus (EBV) is closely associated with many human cancers such as Burkitt's lymphoma, Hodgkin's lymphoma, AIDS-related lymphomas, post-transplant lymphoproliferative disease, cancers of the nose and throat, and stomach cancer. In many of these malignancies, proteins made by EBV are necessary for tumor cells to grow indiscriminately. This is especially true of AIDS-related lymphomas and post-transplant lymphoproliferative disease, which are serious complications of AIDS and transplant surgery. These cancers are responsible for thousands of deaths each year in the United States.

 

The LSUHSC research team, which also includes Kenneth Johnston, PhD, Professor of Microbiology, and Timothy Foster, PhD, Assistant Professor of Microbiology and faculty of the LSUHSC Gene Therapy Program, investigated a small region of a certain Epstein-Barr virus protein called EBNA1, to determine the role it plays in the activation of the EBV genes responsible for the indiscriminate growth of tumor cells in these cancers. Their research shows that EBNA1 is controlled by oxidative stress (pathologic changes in response to excessive levels of free radicals) within the EBV-infected cells. Varying levels of oxidative stress change EBNA1's ability to activate EBV genes responsible for indiscriminate tumor cell growth.

 

"We have shown that in vitro, existing therapeutics such as Vitamin K that can change oxidative stress within cells, inactivate EBNA1," notes Dr. Aiyar, who is also a member of the faculty of the LSUHSC Stanley S. Scott Cancer Center. "As a consequence, EBV genes required for proliferation are no longer expressed, and malignantly transformed cells stop proliferating."

 

The research was funded by grants from the National Cancer Institute, the Louisiana Cancer Research Consortium, and the Department of Microbiology, Immunology, and Parasitology at LSU Health Sciences Center New Orleans School of Medicine.

 

"It is our hope that this research will lead to new ways of controlling EBV-associated diseases in humans," concludes Dr. Aiyar.

 

ABOUT LUSHSC: LSU Health Sciences Center New Orleans educates Louisiana's health care professionals. The state's academic health leader, LSUHSC comprises a School of Medicine, the state's only School of Dentistry, Louisiana's only public School of Public Health, and Schools of Allied Health Professions, Nursing, and Graduate Studies. LSUHSC faculty take care of patients in public and private hospitals and clinics throughout Louisiana. In the vanguard of biosciences research in a number of areas worldwide, LSUHSC faculty have made lifesaving discoveries and continue to work to prevent, better treat, or cure disease.

 

http://newswire.ascribe.org/cgi-bin/behold.pl?ascribeid=20090609.143630&time=17%2000%20PDT&year=2009&public=0

 

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Editorial: Protect education, health care

Daily World | 06.12.09

From staff reports

 

Two sides are doing a lot of talking about the problems that have put Louisiana in a deep budget hole.

 

Whether they will start listening to each other, and what they'll be able to accomplish if they do, are questions yet to be answered. In Louisiana's fouled-up budgeting system, there may be nothing to talk about anyway.

 

A group of Acadiana people with high-ranking positions in education and heath care invited reporters to hear what Gov. Bobby Jindal's proposed budget cuts mean to their companies and institutions. We'd already heard from one of them, UL President Joseph Savoie, who had warned that Lafayette's university is being asked to absorb the equivalent of oil-crunch budget-scrubbing in one year.

 

Alongside Savoie were representatives of the local health-care industry, who sounded warnings of their own. The proposed $450 million cut in fiscal year 2010 health-care spending would reduce funding at Acadiana hospitals by more than $21 million a year.

 

They said those hospitals would be forced to idle 450 employees. Throw in another 50 employees who would lose their jobs at Acadian Ambulance, said CEO Richard Zuschlag. In Lafayette Parish alone, they said, the economy would stand to lose $200 million and 525 jobs.

 

Jindal has a compelling story of his own.

 

Just in case you don't get cable, there's a recession on, and Louisiana unemployment has been creeping upward even though we've been far luckier than other parts of the country. Even so, lower employment will inevitably lower income and sales tax collections even as social welfare spending rises, or should.

 

It wasn't long ago that the Revenue Estimating Conference pegged the price of oil, for revenue-estimating purposes, at a little more than $80 a barrel. At its peak, oil topped $140, so the conference figure seemed absurdly conservative. Nowadays, oil is bumping its head on a $70 ceiling.

 

And, just to rub it in, the federal government is counting every bit of hurricane aid in the per-capita income calculation on which our share of state-federal Medicaid funding is based. So, because we got ravaged by hurricanes Katrina and Rita, the feds will pay less.

 

This isn't just about bad times. It's about a broken state budget system - health care and higher education are being asked to absorb more than $700 million cuts in a single year because other sectors are protected - and a federal Medicaid system with some bizarre ideas about need.

 

Jindal has proposed fixes for both problems, including reduced Medicaid expenditures via partial privatization and more budgeting flexibility for his office and the Legislature. This year's predicament adds urgency to both.

 

http://www.dailyworld.com/article/20090612/OPINION01/906120316

 

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Tables turned on budget

LaPolitics Weekly | 06.12.09

By John Maginnis

 

With a deft maneuver, the House and the governor got the budget they wanted by accepting the Senate’s version of the $28.8 billion spending bill.  Senators, fully expecting a drawn-out conference committee to work out a compromise bill, realized too late they had made a strategic error in crafting their version of the budget that would add more money for higher education and healthcare.

 

The House now has the upper hand because the extra money the Senate added was “below the line,” that is, contingent on passage of two separate revenue-raising bills, which the House opposes.  One is Senate Bill 335 to raise $118 million by freezing the phase-in of personal income tax deductions.  Another would pull $86 million from the so-called rainy day fund, which is more than the governor and the House will commit to.  Without the passage of those revenue measures, the added higher education and healthcare spending is nullified, and the bill becomes much closer to the version the governor proposed and the house first passed.

 

Budget process not over, but narrowed down

 

The budget bill is on its way to the governor’s desk, but the appropriations process is not over.  The governor and House leaders say they can add back up to $70 million for higher education by using one of several smaller special appropriations bills still moving through the process.  The Senate will press to restore more money, but it won’t have the leverage of holding the entire budget hostage in conference committee.  Instead, the differences between the two bodies now amount to less than 1 percent of the spending plan already passed.

 

The trailing funds bill can also include the dozens of member amendments for about $20 million in local grants and projects dear to legislators.  Senators had put those member amendments in the contingency part of the budget bill, thinking that would force the House into negotiations.  They apparently did not anticipate the House using another bill to include those local projects and some new money, though less than the Senate wanted, for higher education.

 

In a released statement, Senate President Joel Chaisson said it will be “a sad day in Louisiana” if the House does not act on the revenue measures.  He further stated that “concurring with House Bill 1 with very limited debate and discussion and no agreement from Senate leadership, is an extremely disappointing development that runs counter to a healthy and honest debate regarding the differences in the House and Senate version of our state budget.”

 

Yet, say representatives, the Senate should not have sent over the bill if it didn’t want the House to accept it, knowing full well the House opposed the contingent revenue bills.  Also, some House members were not happy with Chaisson’s chastising the 55 representatives who signed a letter of opposition to SB 335 before it was debated in the upper chamber.

 

The House has its own revenue measure on the calendar, the 50-cent-per-pack cigarette tax bill.  But procedural motions on it this week gained more than the one-third plus one votes needed to kill it if and when it comes up.

 

While the House move on the budget was a highly unusual one, late-session tensions and resentment between the two bodies are nothing new.

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House agrees with Senate budget but won't back funding

The Town Talk | 06.12.09

By Mike Hasten

Gannett Capitol Bureau

 

BATON ROUGE -- The House of Representatives Thursday unexpectedly concurred with Senate amendments to the budget, even though House leaders said they didn't like the way senators tied many projects to bills that likely won't pass.

 

Rep. Jim Fannin, author of HB1, told House members that many things the Senate version of the bill won't survive because the funding sources, as planned by the Senate, won't be approved. He said the House won't approve freezing a planned increase in income tax deductions and dipping into the "Rainy Day Fund" is questionable.

 

Speaker of the House Jim Tucker refused to send to a committee Senate-passed legislation by Sen. Lydia Jackson, D-Shreveport, that delays the deduction and would save the state $118 million. Tucker says revenue-raising measures must start in the House but Jackson insists it is saving existing money, not raising more.

 

Asked what would happen if the House agreed with the Senate version but didn't approve the way to fund the projects, Fannin replied "they go away."

 

He said other House-passed bills that appropriate money are in the Senate and can be amended to fund things like higher education and health care.

 

Rep. Joel Robideaux, I-Lafayette, a supporter of concurring, said some people in his district hope some of the items do go away. The Senate placed all the non-governmental organization and legislator's preferred projects in the contingency category.

 

"I don't think the public likes member amendments anyway," he said, although he's a bit disappointed to lose the infrastructure projects for the city of Lafayette that he amended into the bill.

 

"Overall, the health of the state's better off" without those $35 million in amendments, Robideaux said. "If that money can be used for higher education, that's better."

 

The original House-passed version included $50 million to restore cuts to higher education by utilizing revenues from a tax amnesty program next year. Senators concerned that the money wouldn't arrive in time to help colleges and universities, chose to utilize "Rainy Day Fund" money instead. The Senate version also allotted higher education and health care, the two section of government hit hardest by budget cuts, money from the tax break delay and a cigarette tax.

 

Those amendments also "go away" without the bills passing.

 

Robideaux said the funding process is "far from finished. In the total process of funding things, a lot's got to happen in the final two weeks."

 

Jindal, after meeting with four previous governors about making higher education a priority, said that he wants to reduce college and university cuts from the proposed $219 million (15 percent) by about $100 million, which he said would be less than a 10 percent cut.

 

Former Gov. Buddy Roemer said he set up the meeting with Jindal after talking with former governors Kathleen Blanco, Mike Foster and Dave Treen because they all were concerned about the proposed cuts.

 

They originally were going to call a press conference without Jindal to express their concerns.

 

Blanco said she wanted to remind Jindal of the importance of higher education.

 

Countering a statement often made by Jindal, Blanco said, "We cannot do more with less. That's an impossible task. You do less with less. That drives us to mediocrity."

 

Blanco, the only Democrat in the group, said she hoped members of the House would "cast some votes that might be difficult."

 

But Jindal said he opposes the revenue-raising proposals and would veto them if approved by the Legislature.

 

Roemer said the former governors "had the feeling something needed to be done" and "what we need is leadership ... Lead, governor. We are prepared to follow."

 

Sen. Robert Adley, R-Benton, said he agrees with the former governors and "if you don't lead, someone else will do it for you. The thing I found ironic is that these were the same governors who Jindal said never provided leadership telling Jindal he needs to lead."

 

Adley said he disagrees with the way the House handled HB1. If the House leadership didn't like it, the bill should have been sent to conference committee to iron out differences "like it always has, like it should have been. It's more than politics. We're dealing with people's lives."

 

Besides House and Senate local projects in the "contingency" section to be funded only if additional revenue was raised, the Senate version includes health care and higher education funds. That section called for $278 million in funding.

 

Rep. Karen Peterson, D-New Orleans, the only opponent who got to speak on the House floor before debate was cut off, said she couldn't cast a vote that would say "just trust me that if you send HB1 to the governor's office, $278 million will be found. Some people have not earned that trust."

 

With juggling funds in other legislation, some things that are normally in the budget will not be in it.

 

Fannin said that although he disagreed with the Senate version, the House should concur because "it's time we sent a message to the other side we work with that this is not the way we do business."

 

Sen. Joe McPherson, D-Woodworth, responded, "I think higher education should send him a message."

 

"I feel like we kind of got railroaded," said Rep. Roy Burrell, D-Shreveport, who during debate questioned the wisdom of approving a budget with no intention of funding parts of it. He also questioned why the administration was veering from its policy of not using one-time revenues to fund recurring expenses.

 

"Just trusting that everything's going to be all right is naïve," he said. "We just handed the budget over and now the governor has full authority to do what he wants. This was a travesty of justice and an extreme disservice to the people we serve."

 

Adley disagrees. He said the House action "took Bobby Jindal out of the process. All he has authority to do is cut. He cannot appropriate funds. He cannot honor his promise to the former governors to reduce higher education cuts below 10 percent without us. It now rests with the Senate and the House how we go."

 

Burrell said he was also disappointed in Speaker of the House Jim Tucker, "who says he wants separation of the legislative and executive branches but he's merging the two" by working so closely with Jindal.

 

Adley said the House acted in "a rush to judgment" and House members didn't have a chance to see what the Senate version really did.

 

Senate President Joel Chaisson, D-Destrehan, said the House action could be read two ways. Either the House agrees to pass the bills required to fully fund the budget, which he applauds, of if it won't act on the proposals, "this is indeed a sad day in Louisiana" because it sets up higher education and health care for "devastating cuts."

 

"Whatever their intentions may have been, concurring in House Bill 1 with very limited debate and discussion and no agreement from Senate leadership is an extremely disappointing development that runs counter to a healthy and honest debate regarding the differences in the House and Senate versions of our state budget," he said.

 

http://www.thetowntalk.com/article/20090612/NEWS01/906120341

 

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Landrieu accused of mixing messages on health care

The Times-Picayune | 06.12.09

By Jonathan Tilove

Washington bureau

 

WASHINGTON -- On the eve of her re-election last fall, Sen. Mary Landrieu, D-La., was approached at a campaign event and asked to sign a letter supporting Health Care for America Now's "statement of common purpose." She obliged.

 

The single-spaced, page-and-a-half letter stated: "Under this approach, everyone gets a choice of health insurance, including the right to keep your current insurance, choose another private plan, or to join a public health insurance plan."

 

This week, however, Landrieu was quoted as saying that she doesn't support the public health insurance plan option.

 

Democratic supporters of the public option howled in outrage even as The Huffington Post Web site, which had reported Landrieu's words of opposition to it, linked to the Health Care for America Now letter signed by Landrieu.

 

Landrieu's office said that the senator has been consistent in her support and co-sponsorship of the bipartisan Wyden-Bennett health plan, which does not include a provision for a public plan. But Landrieu and Wyden both say it will provide universal access to health care coverage on a par that is enjoyed by members of Congress. Landrieu's office suggests that the senator is a victim of, in effect, not reading the fine print of a document thrust at her at a campaign stop.

 

But the folks behind the letter say that, considering how assiduously they had lobbied Landrieu's office on the issue, she should have known what she was signing.

 

Landrieu's office at first questioned the authenticity of the letter linked to by The Huffington Post.

 

But Saunders said they subsequently learned from representatives of the Service Employees International Union -- along with ACORN, the lead Health Care for America Now organizers in New Orleans -- that they had approached the senator with the letter at the campaign event last fall.

 

Saunders said Landrieu had perused the document, endorsed its spirit, and signed.

 

"If you go line by line she agrees with the vast majority" of what is in the letter, Saunders said. "There's just one little line or two that's now being set up as her position on the issue."

 

But, according to Health Care for America Now, that line or two -- repeated twice in the letter -- makes all the difference. The concern of Health Care for America Now and its allies is that a handful of Democratic senators, seeking a bipartisan plan, may spoil the Democrats' chances of getting what they consider truly meaningful reform, including a public option, through Congress. Health Care for America Now has run ads in Oregon trying to persuade Sen. Ron Wyden, D-Ore., to support a public alternative.

 

"What she's doing now is she's dancing around," said Jacki Schechner, the national communications director for Health Care for America Now -- a broad coalition of labor, community, religious and other activist groups -- noting that the organization has been "very, very, very clear" about the crucial role of having a meaningful public alternative.

 

Saunders said that while the Wyden plan does not include a "Medicare-like public option," it does have a federal backup plan to ensure that there are at least two high-quality comprehensive health plans in every state.

 

That's not good enough, Schechner said.

 

Health Care for America Now lists 150 supporters among members of Congress, including Landrieu.

 

Will she now be stricken from the list?

 

"We'll figure it out," Schechner said. "This is not done yet.

 

"We believe that when she looks at health reform more closely," she said, "she will do what's best for the residents of Louisiana and reaffirm her support for the public health insurance option."

 

http://www.nola.com/news/t-p/washington/index.ssf?/base/news-3/124478461282910.xml&coll=1

 

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Budget passes House, but with a twist

WAFB | 06.11.09

By David Spunt

 

BATON ROUGE, LA (WAFB) - After weeks of debate, Governor Bobby Jindal has the state's operating budget on his desk, but the 69-25 approval vote Thursday afternoon by the House is not necessarily a done deal.

 

Usually at this stage in the session, lawmakers are much further behind in the budget process.  That all changed after a surprising move in the House to pass the budget, but two of the biggest sticking points this session, health care and higher education, are both still hanging in the balance.

 

A total of $278 million hinges on the passage of other bills that still haven't been finalized. "The bill that came back to the House was about 98% of what the House sent over to the Senate," said House Speaker Jim Tucker, R-Terrytown.

 

Tucker and 68 of his colleagues passed what they call a bill that will help lower cuts. The 25 who voted against the measure feel they were rushed. "We come in, within five or ten minutes and say, 'This is what we're going to do with the bill. This is how we're going to spend billions of taxpayer dollars, and this is how we're going to cut health care and education,'" said Rep. Juan LaFonta, D-New Orleans. "I just don't think it's a fair process."

 

"I'm committed to making sure higher education has the money needed," Rep Jim Fannin, D-Jonesboro said.

 

Governor Jindal, by law, has ten days to sign the budget. He's expected to use what's called "line item veto" power, where he'll basically go through line by line and cut out what he doesn't want.

 

http://www.wafb.com/Global/story.asp?S=10520770

 

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Former Senate secretary, lawyer Michael Baer, dies

The Advocate | 06.12.09

By MARK BALLARD

Advocate Capitol News Bureau

 

Michael Baer, a lawyer who was the secretary of the Louisiana Senate for 26 years, died Thursday, according to Senate president Joel Chaisson II.

 

Chaisson, D-Destrehan, halted Senate proceedings to note Baer’s passing and called for a moment of silence. The House also observed a moment of silence.

 

The Senate would have a resolution Monday to recognize Baer’s Senate service and government career, Chaisson said.

 

A Senate secretary is the upper chamber’s chief administrator, overseeing the staff that drafts legislation. The secretary also advises the presiding officer on the Senate’s rules.

 

Baer’s career in the Senate ended in 2005. The Senate voted to fire him after he sent a mass e-mail to the Legislature and staff containing vulgar jokes and a sexually suggestive video.

 

Baer said he meant to delete the suggestive e-mail but hit the wrong button.

 

Since leaving the Senate, Baer had handled legal cases for free, said Glenn Koepp, who succeeded Baer as secretary of the Senate.

 

Koepp was Baer’s assistant for about 25 years. The two attended high school in Bogalusa and LSU law school together.

 

Koepp said Baer had a photographic memory and deep knowledge about the history of the Louisiana Senate.

 

“Somebody would have thought they came up with some new unique idea and he would remember something from years and years ago when somebody tried the same thing,” Koepp said.

 

Baer collected exotic birds and loved fishing, he said.

 

He was married twice, Koepp said. With his first wife, Alice, his high school sweetheart, Baer had three children, he said. Baer had two children with his second wife, Debbie, he said.

 

Baer long had health problems. During the legislative session in 1995, Baer suffered chest pains and was treated by then Sen. Don Hines, D-Bunkie, who is a physician, and sent to the hospital on a stretcher.

 

He was back at work the next day.

 

Baer got his start with the Legislature in 1971 when, as a first-year law student, he called his local state senator, B.B. “Sixty” Rayburn, D-Bogalusa, about getting a job.

 

“Without even seeing me, he got me hired for $1.60 a hour as a proofreader with the legislative counsel’s office,” Baer recalled in a 1990 interview. He later worked as a law clerk for former state Rep. Peppi Bruneau, R-New Orleans.

 

Baer served as a legal adviser to former Gov. Edwin Edwards in one capacity or another over the years. He was a law partner of Camille Gravel, one of Edwards’ closest associates. During Edwards’ second term in office, Baer served as counsel to the governor.

 

Baer also served as attorney for the Joint Legislative Committee on the Budget and the Senate Finance Committee before being named secretary.

 

http://www.2theadvocate.com/news/47888442.html

 

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To Flu Experts, ‘Pandemic’ Confirms the Obvious

The New York Times | 06.11.09

By DONALD G. McNEIL Jr. and DENISE GRADY

 

                                                                                                       Mike Clarke/Agence France-Presse — Getty Images

 

The government of Hong Kong on Thursday ordered all primary schools in the city to be closed for two weeks after the first cluster of local swine flu cases was found. Above, kindergarten students at a local school on Thursday.

 

It came as no surprise on Thursday when the World Health Organization declared that the swine flu outbreak had become a pandemic.

 

The disease has reached 74 countries, and probably met the technical definition of a pandemic — or global spread — weeks ago. Nearly 30,000 cases have been reported, but disease experts think hundreds of thousands or millions of people have actually been infected.

 

So the agency made official what had become obvious: that the H1N1 virus is spreading quickly in different parts of the world, and its chief, Dr. Margaret Chan, said, “Further spread is considered inevitable.”

 

The announcement does not mean that the illness, which has been mild in most people, has become any worse. The term pandemic reflects only the geographic spread of a new disease, not its severity. Pandemics typically infect about a third of the world in a year or two, and sometimes strike in successive waves.

 

“Globally, we have good reason to believe that this pandemic, at least in its early days, will be of moderate severity,” said Dr. Chan, director general of the health agency. So far, 144 people have died from H1N1.

 

The decision to raise the pandemic alert from Phase 5 to Phase 6, its highest level, is meant to signal to countries to step up their efforts to deal with the disease.

 

It also means that the health organization is asking drug makers to start making vaccine as quickly as possible, with the hope of having some batches ready by September. Efforts to make a vaccine are under way, and stockpiles of antiviral drugs have been opened. But the agency does not recommend closing borders or restricting travel.

 

“This is not a surprise,” said Dr. Thomas R. Frieden, the new director of the Centers for Disease Control and Prevention. “For all intents and purposes, the United States government has been in Phase 6 of the pandemic for some time now.”

 

Even though the disease has been relatively mild in most people so far, governments must not relax, Dr. Chan said. For one thing, she explained, the virus could change at any time and become more severe.

 

In addition, the illness may take a greater toll when it reaches poor countries with higher rates of malnutrition, AIDS and other diseases that can lower people’s resistance to infection. Dr. Chan said rich countries should help poor ones less able to protect themselves.

 

Even in developed countries, the virus can cause severe and sometimes fatal illness in pregnant women, babies and people with underlying problems like asthma, heart disease, diabetes, obesity and autoimmune diseases. Dr. Frieden said people in those risk groups should seek treatment if they have a fever of at least 100.4, and a cough or a sore throat.

 

A third to half of the severe and fatal cases have occurred in young and middle-aged people who were previously healthy. In contrast, seasonal flu tends to kill the frail elderly.

 

The severity of the new virus does not even approach that of the 1918 one, which killed 40 million to 50 million people worldwide. But even the milder flu pandemics took serious death tolls. The one in 1957 killed two million people, and the 1968 pandemic killed about one million. Seasonal flu, by comparison, kills 250,000 to 500,000 people a year.

 

Countries that have not yet had cases must anticipate them and prepare their health systems to treat patients, Dr. Chan said. Countries in the early stages of outbreaks should try to contain the disease, she said. Those further along, like Mexico, should not let their guard down even if the disease seems to be waning, she added.

 

“The virus can come back in a second wave,” Dr. Chan said. “When you’re over the first wave, start preparing for the future.”

 

The W.H.O. has been questioned sharply for weeks as to why it would not go to Phase 6 even though the spread of cases, first in Britain and Spain, then in Japan, Australia and Chile, seemed to meet its pandemic definition: the sustained community spread of a novel virus in two different W.H.O. regions.

 

Dr. Chan has indicated recently that she thought a pandemic was under way, especially as cases in Australia quadrupled in a week, but she wanted to consult with countries that had large outbreaks and then with a panel of experts on Thursday.

 

From early reports in Mexico and the United States, scientists have said that H1N1 appears to have roughly the same 0.6 percent death level as the 1957 Asian flu. The 1918 flu killed about 2.5 percent of those infected.

 

But in 1918, antibiotics did not exist, and many people died of secondary bacterial infections. In 1957, antiviral drugs did not exist, and mechanical ventilators were less common.

 

Dr. Michael T. Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota, said this year’s flu is not acting like the 1957 one, which quickly faded into a seasonal pattern. There would normally be no flu cases in the United States in June, but flu hospitalizations are increasing in Minnesota, he said.

 

Flu levels continue to be high in New York and New England, and especially in Massachusetts, the C.D.C. said.

 

http://www.nytimes.com/2009/06/12/world/asia/12flu.html?_r=1&ref=health

 

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Medicine in the Age of Twitter

The New York Times | 06.11.09

By PAULINE W. CHEN, M.D.

 

I blog, I tweet and I use Facebook. And as I recently told a medical colleague, social media has been an enormously useful tool in my work.

 

“I can barely keep up with e-mail,” he snorted back. “I’m not about to open up that black box.”

 

About 15 years ago, during my residency and just as the first blogs were starting up, I took care of a patient in his mid-40s whom I’ll call Eddie. In a waiting room filled with elderly patients crippled by vascular disease, Eddie looked out of place. Until you looked closer at his fingers and toes. Parts of them had been amputated.

 

Eddie suffered from Buerger’s disease, or thromboangiitis obliterans, an illness that causes clotting and inflammation of the blood vessels of the hands and feet. Considered an “orphan” disease because of its relative rarity, Buerger’s disease compromises the blood supply to a patient’s fingers and toes. Eventually these patients, who are usually men in their 20s to 40s who smoke, develop excruciating pain, severe ulcerations and gangrene. And more often than not, they must undergo progressively higher amputations.

 

There is no cure for Buerger’s disease; the only way to slow the process is to quit smoking. Therein lies the tragedy. For unknown reasons, patients who suffer from Buerger’s disease are profoundly addicted to tobacco, far more so than most smokers. It is nearly impossible for them to quit.

 

Eddie wanted desperately to quit. Over the two years that I cared for him, he tried at least a dozen times. But his already challenging task was made even more difficult by his isolation. Eddie lived alone, estranged from his family, with friends and co-workers who grew increasingly unsympathetic to his plight. “They don’t understand why I keep smoking if I keep losing fingers,” he said to me one afternoon. “They just don’t understand how hard it is for me.” Moreover, because his disease was so rare, he had no community of fellow patients to turn to in his town or at our hospital.

 

But his visits to the clinic always seemed to cheer him up. He responded, it seemed, to my encouragement, and each time he left, he renewed his vow to quit smoking. But weeks would pass and his enthusiasm would wane. If I contacted him by phone, his momentum might continue another few days, but finding a mutually convenient, quiet moment to talk on a regular basis was exceedingly difficult. I tried scheduling frequent follow-up appointments, but Eddie lived over an hour away from our hospital and could not afford to keep missing work.

 

Eventually, Eddie lost another two fingers, the front half of his left foot and his entire right foot. The youngest man in my waiting room soon became confined to a wheelchair. At the end of our last visit, I stood in the clinic hall watching him inch away from me in that chair, pushing off the ground with the remaining stump of his left foot and grasping at the wheels with hands that had become mitts.

 

I thought about Eddie and other patients I have cared for who might have benefited from more frequent contact when I spoke with my colleague about social media and the patient-doctor relationship. I wondered if Eddie would have felt a little less isolated and perhaps been able to quit smoking if I had, for example, texted a word of encouragement to him every few days, interacted through blog comments, or directed him to an online community of people who were dealing with the exact same disease.

 

A survey released today by the Pew Internet and American Life Project reports that 61 percent of Americans go online for health information, and the majority of them have turned to user-generated health information. But a quick scan through peer-reviewed journals reveals only a handful of articles, and no evidence-based guidelines, to guide doctors on the use of social media. It is unclear whether such engagement adds to or detracts from a therapeutic patient-doctor relationship, and clinicians are unsure about what constitutes good standards of care and professional responsibility on these platforms. For example, should doctors give out diagnoses or prescribe treatment on Facebook or a blog? If doctors and patients communicate on Twitter, is a doctor liable if she or he misses a patient’s tweets about the acute onset of shortness of breath?

 

Dr. Sean Khozin, who blogs and can be found on Twitter @SeanKhozin, is an internist and founding member of Hello Health, a paperless “concierge” practice based in Brooklyn that utilizes e-mail, instant messaging and video chat for coordinating care. “There are so many layers of bureaucracy between health care providers and patients,” Dr. Khozin said. “We can use social media to coordinate care with patients and with different specialists, all using the same platform. I can monitor my patients, and they can also use these tools to become empowered through a better understanding of their own disease state and active engagement.”

 

In Dr. Khozin’s practice, that engagement occurs on a secure site, as patient privacy remains a major concern with all forms of social media. But on platforms such as Twitter and Facebook, where privacy is more difficult to insure, those concerns also extend to physicians. “On the one hand it is really good to see the human side of your doctor on a site like Facebook,” observed Dr. Daniel Sands (@DrDannySands), a physician at Beth Israel Deaconess Medical Center in Boston, Mass., and a consultant with the Cisco Internet Business Solutions Group, as well as co-author of the first set of guidelines ever published on using e-mail in patient care. “On the other hand,” Dr. Sands continued, “maybe letting your patient get too close isn’t always good for the therapeutic relationship.”

 

Taking on the responsibilities of yet another form of communication can also be onerous for physicians, many of whom already feel overburdened by multiple demands on their time. “Physicians are really busy,” Dr. Sands said. “In our current health care environment, the only commodity they have is time. Doctors don’t want to introduce new technologies of unknown value, which is why many were hesitant about e-mail. Something like Twitter is going to take longer to accept because the value proposition is even hazier.”

 

Still, there continues to be anecdotal evidence regarding social media’s potential to strengthen the patient-doctor bond. “One way I see that power is through education,” said Dr. Christian Sinclair, a physician for Kansas City Hospice who has created a palliative care network through his blog and Twitter (@ctsinclair). “I can help to inform the public, I can put the knowledge I have out there. And if there are patients or families who need this knowledge, I can help them because of this network.” Dr. Sinclair has, for example, helped individuals he has met through Twitter connect with local hospices, a process he believes was expedited by Twitter’s particular platform.

 

And social media can also help patients and physicians widen illness support networks, which in turn can augment the patient-doctor relationship. Health care providers have long known that patients with chronic or life-threatening diseases benefit from support groups made up of people who can sympathize and empathize with them. But such support is difficult for physicians or hospitals and clinics to cobble together when patients and families are physically isolated or homebound, or when they have an orphan disease like Eddie’s.

 

“With social media,” Dr. Sands observed, “we can aggregate across space and across the world and create a safe environment for support. Although there may be only 10 people in greater New York with a certain disease, there may be 250 people across the world.” Dr. Sands recalled guiding a patient to the Association of Cancer Online Resources, a social network of online communities for patients and families. “That was the most important advice I ever gave him. It was an information prescription.”

 

Social media platforms can turn 10- or 20-minute doctor’s visits into an ongoing dialogue, where sources of information and, potentially, support are continually available to the patient and the doctor. “Platforms like Twitter can be powerful if doctors are a lot more active in disseminating their expertise,” Dr. Khozin said. “Patients are being bombarded with information online, but I don’t think all that information necessarily empowers them. You also need expertise.”

 

Social media has kept me connected with colleagues and a few former patients, allowed me to stay up-to-date with certain health care and medical education issues, and helped me to keep abreast of Web-based resources that might be useful to those I care for. It has also taught me a tremendous amount about the experiences of patients and caregivers, information I’m not sure I would have had access to had I not been engaged online. Although I am far from a savvy user, I have come to think of social media like I do any other test, instrument or procedure; it’s extremely helpful in some situations, and for some patients, and less so in others.

 

A few days ago, staring at a blank screen and thinking about this column, I tweeted: Working on column on social media (spec. Twitter, Facebook, blogs) and patient-doctor relationship. Any opinions?

 

Minutes later I began to receive replies, including this one from @achronicdose:

 

Knowledge from patient-peers thru social media *can* mean more helpful talks w/ dr; dr. p.o.v. helpful for patients to read.

 

Doctor or patient, you are never alone in the twitterverse or blogosphere; there is always someone who is willing to offer some help or lend some support. It’s a world that I think might have made all the difference for a patient like Eddie.

 

http://www.nytimes.com/2009/06/11/health/11chen.html?ref=health

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Senate Approves Tight Regulation Over Cigarettes

The New York Times | 06.11.09

By DUFF WILSON

 

WASHINGTON — More than four decades after the surgeon general declared smoking a health hazard, the Senate on Thursday cleared the final hurdle to empowering federal officials to regulate cigarettes and other forms of tobacco for the first time.

 

The legislation, which the White House said President Obama would sign as soon as it reached his desk, will enable the Food and Drug Administration to impose potentially strict new controls on the making and marketing of products that eventually kill half their regular users. The House, which passed a similar bill in April, may vote on the Senate version as soon as Friday.

 

“This is a historic step changing the nature of tobacco in society forever,” said Clifford E. Douglas, the director of the University of Michigan Tobacco Research Network, which has extensively studied the health effects of smoking and was one of many groups that have long pushed for tobacco regulation.

 

The Congressional Budget Office has estimated the new law would reduce youth smoking by 11 percent and adult smoking by 2 percent over the next decade, in addition to reductions already achieved through other actions, like higher taxes and smoke-free indoor space laws.

 

The Family Smoking Prevention and Tobacco Control Act, as it is called, stops short of empowering the F.D.A. to outlaw smoking or ban nicotine — strictures that even most antismoking advocates acknowledged were not politically feasible and might drive people addicted to nicotine into a criminal black market.

 

But the law would give the F.D.A. power to set standards that could reduce nicotine content and regulate chemicals in cigarette smoke. The law also bans most tobacco flavorings, which are considered a lure to first-time smokers. Menthol was deferred to later studies. Health advocates predict that F.D.A. standards could eventually reduce some of the 60 carcinogens and 4,000 toxins in cigarette smoke, or make it taste so bad it deters users.

 

The law would also tighten restrictions on the marketing and advertising of tobacco products. Colorful ads and store displays will be replaced by black-and-white-only text. Beginning next year, all outdoor advertising of tobacco within 1,000 feet of schools and playgrounds would be illegal.

 

And cigarette makers will be required to stop using terms like “light” and “low tar” by next year and to place large, graphic health warnings on their packages by 2012.

 

“This is a bill not for a one-year or two-year splash, but for a long-term impact,” said Matthew L. Myers, president of the Campaign for Tobacco-Free Kids, a Washington advocacy group that took a lead in coordinating support for the legislation.

 

Industry analysts say that the imposition of fees on cigarette companies to pay for the creation and administration of a new F.D.A. tobacco oversight department, which could eventually reach 6 cents a pack, could further raise the cost of smoking.

 

Industry analysts, though, predict that federal regulation, like higher taxes, will be manageable for the tobacco companies. As long as they have a market of addicted customers, even if that clientele is dwindling, they can raise prices to remain profitable.

 

The law would be the first big federal step against smoking since the 1971 ban against tobacco advertising on television and radio and the 1988 rules against smoking on airline flights — but potentially much more sweeping than either of those moves.

 

The law might also address the perceived shortcomings of the $206 billion “master settlement” agreement that seven tobacco companies reached with 46 states in 1998 to resolve lawsuits and change their marketing practices. Afterward, cigarette companies nearly doubled their marketing spending and increased their advertising in stores.

 

Although the nation’s smoking rate has gradually declined in recent years, an estimated one in five people in this country still smoke. And more than 400,000 of them die each year from smoking-related disease.

 

For decades, though, despite influential studies in the early 1950s linking smoking to cancer and even after the surgeon general’s report in 1964, Congressional efforts to regulate tobacco met stiff opposition from lawmakers from tobacco-growing states and their political allies.

 

And when the F.D.A. tried on its own to start regulating nicotine as a drug, the Supreme Court struck down that effort in 2000, saying the agency could not take such a step without Congressional authority. Cigarettes remained less regulated than cosmetics or pet food.

 

But this time the antitobacco forces came into alignment, with broad bipartisan support in Congress, where Mr. Obama — himself a smoker who has acknowledged his trouble in quitting the habit — had been a sponsor of the legislation when he was still in the Senate. The Senate passed the bill Thursday by a vote of 79 to 17. The only Democrat voting against it was Kay Hagan of the North Carolina, the leading tobacco-growing state.

 

Another political factor was the willingness of the nation’s biggest tobacco company, Altria Group — owner of Philip Morris and its industry-leading Marlboro brands — to accede to federal regulation. No other tobacco company supported the legislation.

 

Publicly, Altria pushed the legislation for “the greater predictability and stability we think it will bring to the tobacco industry,” as a spokesman, Brendan J. McCormick, said this week.

 

But the impulse dates to the 1990s, when according to Philip Morris documents released during lawsuits, the company decided to remake its image as a responsible corporate citizen. Part of that strategy was to advocate legislation to reduce the risks in cigarettes, and avoid smoking’s being outlawed outright.

 

Moreover, as the industry’s richest company, with profits last year of more than $3 billion, Altria, based in Richmond, Va., has built an extensive scientific research operation. It may thus be the company best equipped to deal with the F.D.A.’s new review process for new, ostensibly safer tobacco products.

 

Under the law, new smokeless tobacco and other products pitched as having lower health risks could be approved only if makers could demonstrate health benefits to society as a whole — meaning the products would not induce too many nonsmokers or would-be quitters to try them, rather than abstaining.

 

As Altria’s competitors have repeatedly argued in opposing the legislation, Altria stands to retain more market share if the advertising crackdown makes it harder for other companies to improve their sales standing.

 

Yet, even Altria said Thursday the legislation, while “an important step forward,” was “not perfect.” The Association of National Advertisers says the act’s “unprecedentedly broad advertising restrictions” violate First Amendment protections for commercial speech. Legal experts say a court challenge on that ground is virtually certain.

 

http://www.nytimes.com/2009/06/12/business/12tobacco.html?ref=health

 

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Drug Appears Safe for Morning Sickness

The New York Times | 06.11.09

By RONI CARYN RABIN

 

Morning sickness is an unavoidable part of pregnancy for most women, but many are reluctant to take medications to quell nausea and vomiting. Now one of the largest studies ever done on a commonly used anti-nausea drug, metoclopramide, has concluded it is safe and does not affect fetal development, even when taken during the first trimester, a critical period of development.

 

The study, released Thursday in The New England Journal of Medicine, analyzed the outcomes of more than 80,000 births in southern Israel over the course of a decade. It found that the 3,458 babies whose mothers were prescribed the drug during the first trimester of pregnancy fared just as well as other babies.

 

They were no more likely to be born with congenital abnormalities or to have other problems, such as being born prematurely, having a low birth weight or dying, the study found.

 

“Our study is about 10 times larger than all of the other studies of this drug put together,” said Dr. Rafael Gorodischer, one of the study’s authors and a professor emeritus of pediatrics at Ben-Gurion University in Israel. “We studied exposure in the first trimester because that is the most critical period for the development of the fetus, when most malformations would be caused by an external cause.”

 

“We can now say with a high degree of confidence that it’s a safe medication,” he said.

 

Metoclopramide is already used to treat severe morning sickness in the United States, where it is commonly sold under the brand name Reglan. But while physicians who care for pregnant women said the results of the new study are reassuring, they said they weren’t likely to prescribe it for run-of-the-mill morning sickness of the kind most women experience at the beginning of pregnancy.

 

For women with mild nausea and vomiting once or twice a day, “There are conservative measures they can try, like eating little bits of food all the time so they always have something in their stomach, using antacids to deal with indigestion, or staying away from caffeine or anything that smells bad to them,” said Dr. Peter Bernstein, a maternal-fetal medicine specialist at Montefiore Medical Center in New York.

 

Still, Dr. Bernstein said the study was strong not just because of its size but because it weighed factors other than malformations, such as birth weight, that also affect the health of the baby.

 

To do the study, researchers analyzed a computerized database of all medications dispensed to women in a health plan in southern Israel from the start of 1998 to the end of March, 2007. They linked that with maternal and infant hospital records during the same period of time, looking at associations between the use of metoclopramide and adverse outcomes in the babies.

 

Some 4.2 percent of the 81,703 babies born during the 10-year period were born to mothers who had been prescribed the drug, but researchers found they were not at increased risk for congenital abnormalities, prematurity, low birth weight or mortality soon after birth. While some 5.3 percent of babies exposed to metoclopramide were born with birth defects, compared with 4.9 percent of those who had not been exposed to the drug, the difference was so small that it could easily have occurred by chance.

 

There were also no significant differences in the risk for low Apgar scores, a series of measures done immediately after birth to assess newborn health, the researchers found.

 

Most of the women were prescribed the equivalent of about a week’s worth of the medication, but researchers were unable to know for sure whether they actually took the drug or not. Additional calculations determined that even babies whose mothers took the drug for more than a week did not face increased risks.

 

Metoclopramide, which has been approved by the Food and Drug Administration, is used to treat gastric problems, nausea and heartburn in adults. Long-term chronic use, however, is associated with tardive dyskinesia, a movement disorder. It is considered a Category B drug, which means it is presumed to be safe to a fetus based on animal studies, though controlled studies of pregnant women have not been done. It is one of several drugs already used in the United States to treat severe nausea and vomiting during pregnancy.

 

http://www.nytimes.com/2009/06/11/health/11nausea.html?ref=health

 

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How a Mild Virus Might Turn Vicious

The New York Times | 06.11.09

By DONALD G. McNEIL Jr.

 

         Miguel Tovar/Associated Press

 

PREVENTION In Mexico City in May, a student wore a mask against swine flu.

 

The swine flu virus is rapidly making its way around the world, but it has been relatively mild so far, causing only 139 confirmed deaths. Could it mutate into something more lethal?

 

Scientists looking at its genetic structure say there is no obvious pressure for it to do so — no reason for this virus to “want,” in the Darwinian sense, to kill more of its hosts.

 

It is already doing a near-perfect job of keeping itself alive by invading human noses and inducing humans to cough it from one to another, said Dr. W. Ian Lipkin, director of the Center for Infection and Immunity at Columbia University’s Mailman School of Public Health.

 

“A really aggressive flu that quickly kills its host” — like SARS and H5N1 avian flu — “gives itself a problem,” Dr. Lipkin said.

 

But flu viruses are highly mutable, and anything could happen in the next two years, the time a new strain normally takes to circle the globe. After all, Spanish influenza began as a mild strain, then turned horrifically virulent, killing 20 million to 100 million people in 1918-19.

 

But Dr. Peter Palese, head of microbiology at Mount Sinai Medical School and part of the team that rebuilt that virus in 2005 from fragments found in old lung tissue, said that strain was a “once-a-millennium or once-every-10-millennia event — things like it don’t happen very often.”

 

Nor is it clear, he added, that viruses really “want” a particular outcome.

 

“For me, that’s too much anthropomorphic thinking,” Dr. Palese said. “Look, I believe in Darwin. Yes, the fittest virus survives. But it’s not clear what the ultimate selection parameter is.”

 

A mutation that confers lethality, he explained, may confer another advantage scientists have not pinned down.

 

The new virus has been described as “a real mutt” by Walter R. Dowdle, the former chief of virology for the Centers for Disease Control and Prevention, because of its unique mix of Eurasian and American swine, human and bird genes.

 

 

Flu chromosomes are quite simple — eight short strands of RNA that issue the genetic code for a grand total of 11 proteins. They break apart in a jumble inside cells they infect, and then they reassemble, picking up random bits of other flus, which makes the results unpredictable.

 

The current swine flu strain lacks several genes believed to increase lethality, including those that code for two proteins known as PB1-F2 and NS-1, and one that codes for a tongue-twister called the polybasic hemagglutinin cleavage site.

 

PB1-F2 appears to weaken the protective membrane of the energy-producing mitochondria in an infected cell, ultimately killing the cell. Specifically, it attacks dendritic cells, the sentinels of the immune system. Its lethality could be accidental — a protein good at killing sentries might just go on killing other cells once inside the fort.

 

All pandemic flus, including those of the Spanish, Hong Kong and Asian flus, make PB1-F2. So does the H5N1 bird flu. The current swine strain does not.

 

The NS-1 protein also maims the immune response by blocking interferon, an antiviral protein made by cells.

 

Very lethal bird flus also have the unusual cleavage site, which allows the hemagglutinin spike on the virus’s shell to split and inject its genetic instructions into different kinds of cells, like those in the lungs and the gut.

 

Such an addition to the novel H1N1 would be very dangerous. But because it has been found only in avian flus, it is unlikely to become a component of a human flu, Dr. Palese said. Even the 1918 virus, which was avian in origin, lacked it.

 

A much more likely change, scientists have said, is that the H1N1 swine flu will become resistant to the antiviral drug Tamiflu. A gene for Tamiflu resistance is now almost universal in seasonal H1N1 flus.

 

If that happens, the world’s Tamiflu stockpiles will be all but worthless, and doctors may have to switch to Relenza, which is a powder used with an inhaler, which makes it more expensive and harder to take.

 

Depending on the mutation, older antiviral drugs like rimantidine may be useful, but so much resistance to them developed in seasonal flu that they were largely abandoned a few years ago.

 

Dr. Palese was asked about another notion concerning likely mutations. There has been outrage at Egypt’s decision to kill all the pigs belonging to its Coptic Christian minority. It has been depicted as misguided and motivated by religious bigotry, because the “swine flu” is really now a human flu.

 

But Egypt is also in an especially dangerous situation. The new swine flu reached it just last week. The H5N1 avian flu has circulated in its backyard chickens since 2006, defying all eradication efforts. In the last year, dozens of H5N1 cases have been confirmed in toddlers, almost all of whom have survived — which led some experts to speculate that those are cases of a less lethal version of H5N1 that is better adapted to humans.

 

In that case, might it be wise to get rid of the country’s relatively small pig population, since pigs are “mixing vessels” that can catch both human and bird flus?

 

“I agree with the premise, if you really could eliminate an animal reservoir,” Dr. Palese said. “But the virus is out of pigs now — and it’s more important that those poor people have something to eat.”

 

http://www.nytimes.com/2009/06/09/health/09flu.html?ref=health

 

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Can Memory Loss Be Prevented?

The New York Times | 06.11.09

By Anne Underwood

 

                                                                                Brandon Thibodeaux for The New York Times

 

Bob Branham, 78, at home with some of his quilting projects. He participates in a study designed to see whether acquiring new skills can stave off dementia.

 

At the age of 78, Bob Branham, a retired computer software developer in Dallas, Tex., took up quilting. It wasn’t his idea, actually. He’d never dreamed of piecing together his own Amish diamond coverlet or rummaging around Jo-Ann Fabrics in search of calico prints. But then he enrolled in a trial sponsored by the National Institute on Aging to assess whether learning a new skill can help preserve cognitive function in old age. By random assignment, he landed in the quilting group.

 

When it comes to mental agility, we’re more likely to think of crosswords than cross-stitch. But neuroscientists suspect that learning a challenging new skill — a new language, a new musical instrument — may be even more effective than mental games at keeping the brain sharp. And quilting is more complicated than it may seem.

 

“It’s a very abstract task,” said Dr. Denise Park, a cognitive neuroscientist at the University of Texas at Dallas, who is leading the trial. “You have to picture what the pattern will look like, match fabrics, manipulate geometric forms, mentally rotate objects.”

 

In Mr. Branham’s case, he also had to learn to use a sewing machine. And while it’s too early to tell if quilting is sharpening his mind, he quickly found that he loved his new pastime. He spends as much as 40 hours a week piecing and stitching, both at home and at the social center that Dr. Park set up for the trial.

 

“I get ideas and pointers from the instructor and the other participants,” he said. “We have a real good time.”

 

Memory is among the least understood areas of neuroscience, and the sad truth is that there is no magic pill or potion at present that will prevent our parents’ minds from failing. But a panel of 30 experts from the United States and Europe recently issued a consensus statement on what we do know about maintaining brain fitness (which includes not only memory, but also reasoning, attention and speed of processing). The verdict was that three things are crucial: physical exercise, mental challenges and good health habits in general.

 

But wait! What about the supplements and software programs we’ve been stocking up on? “There’s a lot of snake oil out there,” warned Dr. Laura Carstensen, director of the Center on Longevity at Stanford University, who co-chaired the panel. In short, don’t count on supplements. (The rationale behind ginkgo biloba is plausible, but there is no scientific evidence it works.) Steer clear of anything that promises to prevent Alzheimer’s disease. (Such a claim would require approval from the Food and Drug Administration, and no product has it.) And look skeptically on software programs. (Most improve performance only on the games themselves, not mental function in general.)

Quilter Bob Branham reaches for a needle.Brandon Thibodeaux for The New York Times

 

Instead, Dr. Carstensen said, get moving. Exercise may sound like an impractical way to boost Mom’s cognition when her energy levels are dwindling. But multiple studies show it helps. In a study published in the Archives of Internal Medicine in 2001, women ages 65 and older who walked the most showed the least cognitive decline over an eight-year period — up to 30 percent less than their sedentary counterparts.

 

Another trial in the journal Nature by Dr. Arthur Kramer, a neuroscientist at the University of Illinois at Urbana-Champaign, found not just slower declines but actual improvements in working memory, attention and executive skills in older adults (average age 72) after six months of an aerobic exercise program — specifically, 45 minutes to an hour of walking, three times a week.

 

How could aerobic exercise possibly accomplish this? Among other things, it increases blood flow, encourages the formation of new synapses and reverses some of the age-related decline in brain volume. “If exercise were a pill, it would be the most expensive drug on the market,” said Dr. Carstensen.

 

Other good habits are important, too. As neuroscientists like to say, what’s good for the heart is good for the brain. That would include maintaining healthy blood sugar and blood pressure levels. A study last December in the Annals of Neurology showed that controlling blood sugar, even in non-diabetic adults, can help prevent deterioration in a part of the brain that’s necessary for memory formation. Another paper published in the Archives of Neurology in February by scientists at Columbia University found that eating a heart-healthy Mediterranean diet — rich in fish, vegetables, whole grains, fruits, legumes and unsaturated fats — lowered the risk of mild cognitive impairment over four and a half years by as much as 28 percent.

 

But even if Mom follows all the advice she herself used to propound — eat your vegetables, go outside and exercise — there is no substitute for mental challenges. The brain is a use-it-or-lose-it type of organ. Synaptic connections that aren’t firing will weaken.

 

The problem with most of our favorite approaches to staying sharp is that they are narrowly focused when what’s needed is global improvement. Crosswords are great for word retrieval. That’s clearly important. But not even The Times’s Sunday puzzle by Will Shortz will help you remember where you left your car keys. “If you want lots of improvement, you have to do mental cross-training,” said Dr. K. Warner Schaie, a professor of psychology at Pennsylvania State University.

 

In short, engage in many types of mental activity. Do crosswords, Sudoku, acrostics, play bridge, read books, join clubs, get into debates, volunteer — anything to keep the mind alive and engaged in new and interesting tasks. If the activity includes social interaction, so much the better. Or take up a new hobby, a new language or a new instrument that will challenge the brain in entirely different ways, preferably for years. “One problem with aging is that you develop expertise in a few things and do them over and over,” said Dr. Carstensen. “Proficiency is good, but it’s probably not growing new synapses.”

 

Mr. Branham, on the other hand, seems to be sprouting plenty of neural connections. He’s now completed two full-sized quilts — one a sampler with various patterns, the other a split rail design with stars in the four corners. He’d even like to launch a small business selling his patchwork place mats and table runners. When friends at church ask him why he signed up for such a study, and why on earth he agreed to start quilting, he has a ready answer. “Studies need participants,” he says. “And you should sign up, too.”

 

http://newoldage.blogs.nytimes.com/2009/06/11/can-dementia-be-prevented/

 

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